Sirt1 inhibits renal tubular cell epithelial–mesenchymal transition through YY1 deacetylation in diabetic nephropathy

Silent information regulator 1 (Sirt1) is a deacetylase, which plays an important role in the occurrence and development of diabetic nephropathy (DN). Our previous study shows that Yin yang 1 (YY1), a widely expressed zinc finger DNA/RNA-binding transcription factor, is a novel regulator of renal fi...

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Publicado no:Acta Pharmacol Sin
Main Authors: Du, Lei, Qian, Xuan, Li, Yuan, Li, Xi-zhi, He, Lin-lin, Xu, Liu, Liu, Yi-qi, Li, Cheng-cheng, Ma, Pu, Shu, Fang-lin, Lu, Qian, Yin, Xiao-xing
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Singapore 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8027604/
https://ncbi.nlm.nih.gov/pubmed/32555442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41401-020-0450-2
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