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Mammalian histones facilitate antimicrobial synergy by disrupting the bacterial proton gradient and chromosome organization

First proposed as antimicrobial agents, histones were later recognized for their role in condensing chromosomes. Histone antimicrobial activity has been reported in innate immune responses. However, how histones kill bacteria has remained elusive. The co-localization of histones with antimicrobial p...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Nat Commun
Asıl Yazarlar: Doolin, Tory, Amir, Henry M., Duong, Leora, Rosenzweig, Rachel, Urban, Lauren A., Bosch, Marta, Pol, Albert, Gross, Steven P., Siryaporn, Albert
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7403156/
https://ncbi.nlm.nih.gov/pubmed/32753666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-17699-z
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