The ASCT/SCS cycle fuels mitochondrial ATP and acetate production in Trypanosoma brucei

Acetate:succinate CoA transferase (ASCT) is a mitochondrial enzyme that catalyzes the production of acetate and succinyl-CoA, which is coupled to ATP production with succinyl-CoA synthetase (SCS) in a process called the ASCT/SCS cycle. This cycle has been studied in Trypanosoma brucei (T. brucei), a...

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Veröffentlicht in:Biochim Biophys Acta Bioenerg
Hauptverfasser: Mochizuki, Kota, Inaoka, Daniel Ken, Mazet, Muriel, Shiba, Tomoo, Fukuda, Keisuke, Kurasawa, Hana, Millerioux, Yoann, Boshart, Michael, Balogun, Emmanuel O., Harada, Shigeharu, Hirayama, Kenji, Bringaud, Frédéric, Kita, Kiyoshi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier B.V. 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7402102/
https://ncbi.nlm.nih.gov/pubmed/32763239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbabio.2020.148283
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