טוען...
Variable expression and silencing of CRISPR-Cas9 targeted transgenes identifies the AAVS1 locus as not an entirely safe harbour
Background: Diseases such as hypertrophic cardiomyopathy (HCM) can lead to severe outcomes including sudden death. The generation of human induced pluripotent stem cell (hiPSC) reporter lines can be useful for disease modelling and drug screening by providing physiologically relevant in vitro models...
שמור ב:
| הוצא לאור ב: | F1000Res |
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| Main Authors: | , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
F1000 Research Limited
2020
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7401084/ https://ncbi.nlm.nih.gov/pubmed/32789000 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.19894.2 |
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