Simplified Footprint-Free Cas9/CRISPR Editing of Cardiac-Associated Genes in Human Pluripotent Stem Cells

Modeling disease with human pluripotent stem cells (hPSCs) is hindered because the impact on cell phenotype from genetic variability between individuals can be greater than from the pathogenic mutation. While “footprint-free” Cas9/CRISPR editing solves this issue, existing approaches are inefficient...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:Stem Cells Dev
Hoofdauteurs: Kondrashov, Alexander, Hoang, Minh Duc, Smith, James G.W., Bhagwan, Jamie R., Duncan, Gary, Mosqueira, Diogo, Munoz, Maria Barbadillo, Vo, Nguyen T.N., Denning, Chris
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Mary Ann Liebert, Inc. 2018
Onderwerpen:
Original Research Reports
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5882176/
https://ncbi.nlm.nih.gov/pubmed/29402189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2017.0268
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items