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Effect of lysine side chain length on histone lysine acetyltransferase catalysis

Histone lysine acetyltransferase (KAT)-catalyzed acetylation of lysine residues in histone tails plays a key role in regulating gene expression in eukaryotes. Here, we examined the role of lysine side chain length in the catalytic activity of human KATs by incorporating shorter and longer lysine ana...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Proietti, Giordano, Wang, Yali, Rainone, Giorgio, Mecinović, Jasmin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7400623/
https://ncbi.nlm.nih.gov/pubmed/32747680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-69510-0
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