Increased IL-2 and Reduced TGF-β Upon T-Cell Stimulation are Associated with GM-CSF Upregulation in Multiple Immune Cell Types in Multiple Sclerosis

Granulocyte macrophage colony stimulating factor (GM-CSF) is a pro-inflammatory cytokine produced by immune cells. Recent evidence suggests that GM-CSF plays an important role in multiple sclerosis (MS) pathogenesis. We investigated the expression and regulation of GM-CSF in different immune cells i...

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Pubblicato in:Biomedicines
Autori principali: Aram, Jehan, Frakich, Nanci, Morandi, Elena, Alrouji, Mohammed, Samaraweera, Amal, Onion, David, Spendlove, Ian, Colombo, Sergio L., Tanasescu, Radu, Gran, Bruno, Constantinescu, Cris S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7400438/
https://ncbi.nlm.nih.gov/pubmed/32708498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines8070226
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