Therapeutic Targeting of Lewis(y) and Lewis(b) with a Novel Monoclonal Antibody 692/29

Por Noble, Philip, Spendlove, Ian, Harding, Stephen, Parsons, Tina, Durrant, Lindy G.
Publicado em 2013

High expression of Lewis(y/b )antigens is associated with decreased survival in lymph node negative breast carcinomas

Por Madjd, Zahra, Parsons, Tina, Watson, Nicholas FS, Spendlove, Ian, Ellis, Ian, Durrant, Lindy G
Publicado em 2005

Evidence that the p53 negative / Bcl-2 positive phenotype is an independent indicator of good prognosis in colorectal cancer: A tissue microarray study of 460 patients

Por Ellis Ian O, Spendlove Ian, Scrimegour Duncan, Madjd Zahra, Watson Nicholas FS, Scholefield John H, Durrant Lindy G
Publicado em 2005-07-01

Evidence that the p53 negative / Bcl-2 positive phenotype is an independent indicator of good prognosis in colorectal cancer: A tissue microarray study of 460 patients

Por Watson, Nicholas FS, Madjd, Zahra, Scrimegour, Duncan, Spendlove, Ian, Ellis, Ian O, Scholefield, John H, Durrant, Lindy G
Publicado em 2005

Upregulation of MICA on high-grade invasive operable breast carcinoma

Por Madjd, Zahra, Spendlove, Ian, Moss, Robert, Bevin, Shaun, Pinder, Sarah E., Watson, Nicholas F. S., Ellis, Ian, Durrant, Lindy G.
Publicado em 2007

Connexin 43 is an independent predictor of patient outcome in breast cancer patients

Por Chasampalioti, Maria, Green, Andrew R., Ellis, Ian O., Rakha, Emad A., Jackson, Andrew M., Spendlove, Ian, Ramage, Judith M.
Publicado no Breast Cancer Res Treat (2018)

Cytoplasmic expression of p27(kip1) is associated with a favourable prognosis in colorectal cancer patients

Por Watson, Nicholas FS, Durrant, Lindy G, Scholefield, John H, Madjd, Zahra, Scrimgeour, Duncan, Spendlove, Ian, Ellis, Ian O, Patel, Poulam M
Publicado em 2006

The terminal sialic acid of stage-specific embryonic antigen-4 has a crucial role in binding to a cancer-targeting antibody

Por Soliman, Caroline, Chua, Jia Xin, Vankemmelbeke, Mireille, McIntosh, Richard S., Guy, Andrew J., Spendlove, Ian, Durrant, Lindy G., Ramsland, Paul A.
Publicado no J Biol Chem (2020)

High mobility group protein B1 is a predictor of poor survival in ovarian cancer

Por Machado, Lee R., Moseley, Paul M., Moss, Robert, Deen, Suha, Nolan, Christopher, Spendlove, Ian, Ramage, Judith M., Chan, Stephen YT., Durrant, Lindy G.
Publicado no Oncotarget (2017)

Increased IL-2 and Reduced TGF-β Upon T-Cell Stimulation are Associated with GM-CSF Upregulation in Multiple Immune Cell Types in Multiple Sclerosis

Por Aram, Jehan, Frakich, Nanci, Morandi, Elena, Alrouji, Mohammed, Samaraweera, Amal, Onion, David, Spendlove, Ian, Colombo, Sergio L., Tanasescu, Radu, Gran, Bruno, Constantinescu, Cris S.
Publicado no Biomedicines (2020)

The Ataxia Telangiectasia Mutated Kinase pathway Regulates IL-23 Expression by Human Dendritic Cells

Por Wang, Qunwei, Franks, Hester A, Foan, Stephanie, Refaee, Mohamed El, Malecka, Anna, Shah, Sabaria, Spendlove, Ian, Gough, Michael J, Seedhouse, Claire, Madhusudan, Srinivasan, Patel, Poulam M, Jackson, Andrew M
Publicado em 2013

Stromal fibroblasts support dendritic cells to maintain IL-23/Th17 responses after exposure to ionizing radiation

Por Malecka, Anna, Wang, Qunwei, Shah, Sabaria, Sutavani, Ruhcha V., Spendlove, Ian, Ramage, Judith M., Greensmith, Julie, Franks, Hester A., Gough, Michael J., Saalbach, Anja, Patel, Poulam M., Jackson, Andrew M.
Publicado no J Leukoc Biol (2016)

Engineering the human Fc-region enables direct cell killing by cancer glycan-targeting antibodies without the need for immune effector cells or complement

Por Vankemmelbeke, Mireille, McIntosh, Richard S., Chua, Jia Xin, Kirk, Thomas, Daniels, Ian, Patsalidou, Marilena, Moss, Robert, Parsons, Tina, Scott, David, Harris, Gemma, Ramage, Judith M., Spendlove, Ian, Durrant, Lindy G.
Publicado no Cancer Res (2020)

The chromosome 3p21.3-encoded gene, LIMD1, is a critical tumor suppressor involved in human lung cancer development

Por Sharp, Tyson V., Al-Attar, Ahmad, Foxler, Daniel E., Ding, Li, de A. Vallim, Thomas Q., Zhang, Yining, Nijmeh, Hala S., Webb, Thomas M., Nicholson, Andrew G., Zhang, Qunyuan, Kraja, Aldi, Spendlove, Ian, Osborne, John, Mardis, Elaine, Longmore, Gregory D.
Publicado em 2008

A HIF–LIMD1 negative feedback mechanism mitigates the pro‐tumorigenic effects of hypoxia

Por Foxler, Daniel E, Bridge, Katherine S, Foster, John G, Grevitt, Paul, Curry, Sean, Shah, Kunal M, Davidson, Kathryn M, Nagano, Ai, Gadaleta, Emanuela, Rhys, Hefin I, Kennedy, Paul T, Hermida, Miguel A, Chang, Ting‐Yu, Shaw, Peter E, Reynolds, Louise E, McKay, Tristan R, Wang, Hsei‐Wei, Ribeiro, Paulo S, Plevin, Michael J, Lagos, Dimitris, Lemoine, Nicholas R, Rajan, Prabhakar, Graham, Trevor A, Chelala, Claude, Hodivala‐Dilke, Kairbaan M, Spendlove, Ian, Sharp, Tyson V
Publicado no EMBO Mol Med (2018)