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Therapeutic Targeting of Lewis(y) and Lewis(b) with a Novel Monoclonal Antibody 692/29

BACKGROUND: Several monoclonal antibodies (mAbs) recognising Lewis(y), such as BR96, have reached the clinic but have failed to show good anti-tumour responses with an acceptable level of toxicity. No Lewis(b) mAbs have been trialled in patients. In this study we compare the specificity of three mAb...

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Bibliografiska uppgifter
Huvudupphovsmän: Noble, Philip, Spendlove, Ian, Harding, Stephen, Parsons, Tina, Durrant, Lindy G.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2013
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3568143/
https://ncbi.nlm.nih.gov/pubmed/23408949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0054892
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