The chromosome 3p21.3-encoded gene, LIMD1, is a critical tumor suppressor involved in human lung cancer development

Loss of heterozygosity (LOH) and homozygous deletions at chromosome 3p21.3 are common in both small and nonsmall cell lung cancers, indicating the likely presence of tumor suppressor genes (TSGs). Although genetic and epigenetic changes within this region have been identified, the functional signifi...

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Detalhes bibliográficos
Principais autores: Sharp, Tyson V., Al-Attar, Ahmad, Foxler, Daniel E., Ding, Li, de A. Vallim, Thomas Q., Zhang, Yining, Nijmeh, Hala S., Webb, Thomas M., Nicholson, Andrew G., Zhang, Qunyuan, Kraja, Aldi, Spendlove, Ian, Osborne, John, Mardis, Elaine, Longmore, Gregory D.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2604919/
https://ncbi.nlm.nih.gov/pubmed/19060205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0805003105
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