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Interaction of Oxidative Stress and Misfolded Proteins in the Mechanism of Neurodegeneration

Aggregation of the misfolded proteins β-amyloid, tau, huntingtin, and α-synuclein is one of the most important steps in the pathology underlying a wide spectrum of neurodegenerative disorders, including the two most common ones—Alzheimer’s and Parkinson’s disease. Activity and toxicity of these prot...

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Bibliografiske detaljer
Udgivet i:Life (Basel)
Main Authors: Abramov, Andrey Y., Potapova, Elena V., Dremin, Viktor V., Dunaev, Andrey V.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7400128/
https://ncbi.nlm.nih.gov/pubmed/32629809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/life10070101
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