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Liver-specific Prkn knockout mice are more susceptible to diet-induced hepatic steatosis and insulin resistance
OBJECTIVE: PARKIN is an E3 ubiquitin ligase that regulates mitochondrial quality control through a process called mitophagy. Recent human and rodent studies suggest that loss of hepatic mitophagy may occur during the pathogenesis of obesity-associated fatty liver and contribute to changes in mitocho...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Mol Metab |
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| Κύριοι συγγραφείς: | , , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Elsevier
2020
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7399260/ https://ncbi.nlm.nih.gov/pubmed/32653576 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2020.101051 |
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