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CTCF-promoted RNA polymerase II pausing links DNA methylation to splicing
Alternative splicing of pre-messenger RNA is a key feature of transcriptome expansion in eukaryotic cells, yet its regulation is poorly understood. Spliceosome assembly occurs co-transcriptionally, raising the possibility that DNA structure may directly influence alternative splicing. Supporting suc...
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| Vydáno v: | Nature |
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| Hlavní autoři: | , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2011
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7398428/ https://ncbi.nlm.nih.gov/pubmed/21964334 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10442 |
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