CTCF-promoted RNA polymerase II pausing links DNA methylation to splicing

Alternative splicing of pre-messenger RNA is a key feature of transcriptome expansion in eukaryotic cells, yet its regulation is poorly understood. Spliceosome assembly occurs co-transcriptionally, raising the possibility that DNA structure may directly influence alternative splicing. Supporting suc...

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Vydáno v:Nature
Hlavní autoři: Shukla, Sanjeev, Kavak, Ersen, Gregory, Melissa, Imashimizu, Masahiko, Shutinoski, Bojan, Kashlev, Mikhail, Oberdoerffer, Philipp, Sandberg, Rickard, Oberdoerffer, Shalini
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7398428/
https://ncbi.nlm.nih.gov/pubmed/21964334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10442
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