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CTCF-promoted RNA polymerase II pausing links DNA methylation to splicing
Alternative splicing of pre-messenger RNA is a key feature of transcriptome expansion in eukaryotic cells, yet its regulation is poorly understood. Spliceosome assembly occurs co-transcriptionally, raising the possibility that DNA structure may directly influence alternative splicing. Supporting suc...
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| 出版年: | Nature |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7398428/ https://ncbi.nlm.nih.gov/pubmed/21964334 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10442 |
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