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Use of Human Induced Pluripotent Stem Cell–Derived Cardiomyocytes in Preclinical Cancer Drug Cardiotoxicity Testing: A Scientific Statement From the American Heart Association

It is now well recognized that many lifesaving oncology drugs may adversely affect the heart and cardiovascular system, including causing irreversible cardiac injury that can result in reduced quality of life. These effects, which may manifest in the short term or long term, are mechanistically not...

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Detalhes bibliográficos
Publicado no:Circ Res
Main Authors: Gintant, Gary, Burridge, Paul, Gepstein, Lior, Harding, Sian, Herron, Todd, Hong, Charles, Jalife, José, Wu, Joseph C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7398423/
https://ncbi.nlm.nih.gov/pubmed/31533542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/RES.0000000000000291
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