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The case for induced pluripotent stem cell-derived cardiomyocytes in pharmacological screening

The current drug screening models are deficient, particularly in detecting cardiac side effects. Human stem cell-derived cardiomyocytes could aid both early cardiotoxicity detection and novel drug discovery. Work over the last decade has generated human embryonic stem cells as potentially accurate s...

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Detalles Bibliográficos
Main Authors: Khan, Jaffar M, Lyon, Alexander R, Harding, Sian E
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Publishing Ltd 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3651657/
https://ncbi.nlm.nih.gov/pubmed/22845396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2012.02118.x
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