Mechano-Pharmacological Characterization of Cardiomyocytes Derived from Human Induced Pluripotent Stem Cells

Background/Aims: Common systems for the quantification of cellular contraction rely on animal-based models, complex experimental setups or indirect approaches. The herein presented CellDrum technology for testing mechanical tension of cellular monolayers and thin tissue constructs has the potential...

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Bibliographic Details
Main Authors: Matthias Goßmann, Ralf Frotscher, Peter Linder, Stephan Neumann, Robin Bayer, Matthias Epple, Manfred Staat, Ayșegül (Temiz) Artmann, Gerhard M. Artmann
Format: Artigo
Language:Inglês
Published: Cell Physiol Biochem Press GmbH & Co KG 2016-03-01
Series:Cellular Physiology and Biochemistry
Subjects:
Cardiac myocytes
CellDrum
Ion channels
Pharmacology
Inotropic compounds
Induced pluripotent stem cells
Heart tissue culture
Online Access:http://www.karger.com/Article/FullText/443124
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