NK cell receptor NKG2D enforces proinflammatory features and pathogenicity of Th1 and Th17 cells

NKG2D is a danger sensor expressed on different subsets of innate and adaptive lymphocytes. Despite its established role as a potent activator of the immune system, NKG2D-driven regulation of CD4(+) T helper (Th) cell–mediated immunity remains unclear. In this study, we demonstrate that NKG2D modula...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Babic, Marina, Dimitropoulos, Christoforos, Hammer, Quirin, Stehle, Christina, Heinrich, Frederik, Sarsenbayeva, Assel, Eisele, Almut, Durek, Pawel, Mashreghi, Mir-Farzin, Lisnic, Berislav, Van Snick, Jacques, Löhning, Max, Fillatreau, Simon, Withers, David R., Gagliani, Nicola, Huber, Samuel, Flavell, Richard A., Polic, Bojan, Romagnani, Chiara
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7398170/
https://ncbi.nlm.nih.gov/pubmed/32453422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20190133
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