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Assessment of statistical methods from single cell, bulk RNA-seq, and metagenomics applied to microbiome data

BACKGROUND: The correct identification of differentially abundant microbial taxa between experimental conditions is a methodological and computational challenge. Recent work has produced methods to deal with the high sparsity and compositionality characteristic of microbiome data, but independent be...

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Detalhes bibliográficos
Publicado no:Genome Biol
Main Authors: Calgaro, Matteo, Romualdi, Chiara, Waldron, Levi, Risso, Davide, Vitulo, Nicola
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7398076/
https://ncbi.nlm.nih.gov/pubmed/32746888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-020-02104-1
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