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Pancreatic cancer resistance conferred by stellate cells: looking for new preclinical models
Pancreatic ductal adenocarcinoma (PDAC) has an extremely poor response to chemo- and (modest-dose conventionally fractionated) radio-therapy. Emerging evidence suggests that pancreatic stellate cells (PSCs) secrete deoxycytidine, which confers resistance to gemcitabine. In particular, deoxycytidine...
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| Publicado no: | Exp Hematol Oncol |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7398063/ https://ncbi.nlm.nih.gov/pubmed/32775041 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40164-020-00176-0 |
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