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Role of Akt signaling in resistance to DNA-targeted therapy

The Akt signal transduction pathway controls most hallmarks of cancer. Activation of the Akt cascade promotes a malignant phenotype and is also widely implicated in drug resistance. Therefore, the modulation of Akt activity is regarded as an attractive strategy to enhance the efficacy of cancer ther...

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Foilsithe in:World J Clin Oncol
Main Authors: Avan, Abolfazl, Narayan, Ravi, Giovannetti, Elisa, Peters, Godefridus J
Formáid: Artigo
Teanga:Inglês
Foilsithe: Baishideng Publishing Group Inc 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5056327/
https://ncbi.nlm.nih.gov/pubmed/27777878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5306/wjco.v7.i5.352
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