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USP1 deubiquitinase: cellular functions, regulatory mechanisms and emerging potential as target in cancer therapy

Reversible protein ubiquitination is emerging as a key process for maintaining cell homeostasis, and the enzymes that participate in this process, in particular E3 ubiquitin ligases and deubiquitinases (DUBs), are increasingly being regarded as candidates for drug discovery. Human DUBs are a group o...

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Bibliographische Detailangaben
Hauptverfasser: García-Santisteban, Iraia, Peters, Godefridus J, Giovannetti, Elisa, Rodríguez, Jose Antonio
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3750636/
https://ncbi.nlm.nih.gov/pubmed/23937906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-12-91
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