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Two Nuclear Localization Signals in USP1 Mediate Nuclear Import of the USP1/UAF1 Complex

The human deubiquitinase USP1 plays important roles in cancer-related processes, such as the DNA damage response, and the maintenance of the undifferentiated state of osteosarcoma cells. USP1 deubiquitinase activity is critically regulated by its interaction with the WD40 repeat-containing protein U...

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Autori principali: Garcia-Santisteban, Iraia, Zorroza, Kerman, Rodriguez, Jose Antonio
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3368879/
https://ncbi.nlm.nih.gov/pubmed/22701671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038570
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