Role of c-MET Inhibitors in Overcoming Drug Resistance in Spheroid Models of Primary Human Pancreatic Cancer and Stellate Cells

Pancreatic stellate cells (PSCs) are a key component of tumor microenvironment in pancreatic ductal adenocarcinoma (PDAC) and contribute to drug resistance. c-MET receptor tyrosine kinase activation plays an important role in tumorigenesis in different cancers including PDAC. In this study, effects...

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Bibliografiska uppgifter
I publikationen:Cancers (Basel)
Huvudupphovsmän: Firuzi, Omidreza, Che, Pei Pei, El Hassouni, Btissame, Buijs, Mark, Coppola, Stefano, Löhr, Matthias, Funel, Niccola, Heuchel, Rainer, Carnevale, Ilaria, Schmidt, Thomas, Mantini, Giulia, Avan, Amir, Saso, Luciano, Peters, Godefridus J., Giovannetti, Elisa
Materialtyp: Artigo
Språk:Inglês
Publicerad: MDPI 2019
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6562408/
https://ncbi.nlm.nih.gov/pubmed/31072019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11050638
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