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Alternative Allosteric Mechanisms Can Regulate the Substrate and E2 in SUMO Conjugation

Sumoylation is the covalent attachment of small ubiquitin-like modifier (SUMO) to a target protein. Similar to other ubiquitin-like pathways, three enzyme types are involved that act in succession: an activating enzyme (E1), a conjugating enzyme (E2), and a ligase (E3). To date, unlike other ubiquit...

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Dades bibliogràfiques
Publicat a:J Mol Biol
Autors principals: Karaca, Ezgi, Tozluoğlu, Melda, Nussinov, Ruth, Haliloğlu, Türkan
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7398049/
https://ncbi.nlm.nih.gov/pubmed/21216249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.12.044
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