High Levels of Chromosomal Copy Number Alterations and TP53 Mutations Correlate with Poor Outcome in Younger Breast Cancer Patients

Prognosis in young patients with breast cancer is generally poor, yet considerable differences in clinical outcomes between individual patients exist. To understand the genetic basis of the disparate clinical courses, tumors were collected from 34 younger women, 17 with good and 17 with poor outcome...

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Publicado no:Am J Pathol
Main Authors: Koçak, Ayla, Heselmeyer-Haddad, Kerstin, Lischka, Annette, Hirsch, Daniela, Fiedler, David, Hu, Yue, Doberstein, Natalie, Torres, Irianna, Chen, Wei-Dong, Gertz, E. Michael, Schäffer, Alejandro A., Freitag-Wolf, Sandra, Kirfel, Jutta, Auer, Gert, Habermann, Jens K., Ried, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7397461/
https://ncbi.nlm.nih.gov/pubmed/32416097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2020.04.015
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