Aneuploidy, TP53 mutation, and amplification of MYC correlate with increased intratumor heterogeneity and poor prognosis of breast cancer patients

The clinical course of breast cancer varies from one patient to another. Currently, the choice of therapy relies on clinical parameters and histological and molecular tumor features. Alas, these markers are informative in only a subset of patients. Therefore, additional predictors of disease outcome...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Genes Chromosomes Cancer
Prif Awduron: Oltmann, Johanna, Heselmeyer-Haddad, Kerstin, Hernandez, Leanora S., Meyer, Rüdiger, Torres, Irianna, Hu, Yue, Doberstein, Natalie, Killian, J. Keith, Petersen, David, Zhu, Y. Jack, Edelman, Daniel C., Meltzer, Paul S., Schwartz, Russell, Gertz, E. Michael, Schäffer, Alejandro A., Auer, Gert, Habermann, Jens K., Ried, Thomas
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2018
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5807164/
https://ncbi.nlm.nih.gov/pubmed/29181861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gcc.22515
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