In Vitro Antimycobacterial Activity and Physicochemical Characterization of Diaryl Ether Triclosan Analogues as Potential InhA Reductase Inhibitors

Two sets of diphenyl ether derivatives incorporating five-membered 1,3,4-oxadiazoles, and their open-chain aryl hydrazone analogs were synthesized in good yields. Most of the synthesized compounds showed promising in vitro antimycobacterial activity against Mycobacterium tuberculosis H37Rv. Three di...

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Publicado no:Molecules
Main Authors: Ibrahim, Tarek S., Taher, Ehab S., Samir, Ebtihal, M. Malebari, Azizah, Khayyat, Ahdab N., Mohamed, Mamdouh F. A., Bokhtia, Riham M., AlAwadh, Mohammed A., Seliem, Israa A., Asfour, Hani Z., Alhakamy, Nabil A., Panda, Siva S., AL-Mahmoudy, Amany M. M.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7397076/
https://ncbi.nlm.nih.gov/pubmed/32650556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25143125
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