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Patient-derived xenograft (PDX) models: characteristics and points to consider for the process of establishment

Tumor research has largely relied on xenograft models created by the engraftment of cultured cell lines derived from tumor tissues into immunodeficient mice for in vivo studies. Like in vitro models, such models retain the ability of tumor cells to continuously proliferate, so they have been used to...

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Detalhes bibliográficos
Publicado no:J Toxicol Pathol
Main Authors: Fujii, Etsuko, Kato, Atsuhiko, Suzuki, Masami
Formato: Artigo
Idioma:Inglês
Publicado em: Japanese Society of Toxicologic Pathology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7396735/
https://ncbi.nlm.nih.gov/pubmed/32764840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1293/tox.2020-0007
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