Application of Highly Immunocompromised Mice for the Establishment of Patient-Derived Xenograft (PDX) Models

Patient-derived xenograft (PDX) models are created by engraftment of patient tumor tissues into immunocompetent mice. Since a PDX model retains the characteristics of the primary patient tumor including gene expression profiles and drug responses, it has become the most reliable in vivo human cancer...

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Bibliographic Details
Published in:Cells
Main Authors: Okada, Seiji, Vaeteewoottacharn, Kulthida, Kariya, Ryusho
Format: Artigo
Language:Inglês
Published: MDPI 2019
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6721637/
https://ncbi.nlm.nih.gov/pubmed/31412684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8080889
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