Deregulation of Polycomb Repressive Complex-2 in Mantle Cell Lymphoma Confers Growth Advantage by Epigenetic Suppression of cdkn2b

The polycomb repressive complex 2 (PRC2) maintains the transcriptional repression of target genes through its catalytic component enhancer of zeste homolog 2 (EZH2). Through modulating critical gene expression, EZH2 also plays a role in cancer development and progression by promoting cancer cell sur...

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Vydáno v:Front Oncol
Hlavní autoři: Demosthenous, Christos, Gupta, Shiv K., Sun, Jing, Wang, Yongsen, Troska, Tammy P., Gupta, Mamta
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
Témata:
Oncology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7396700/
https://ncbi.nlm.nih.gov/pubmed/32850364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.01226
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