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Frequent epigenetic alterations in polycomb repressive complex 2 in osteosarcoma cell lines

Osteosarcoma (OS) cell lines are widely used in understanding the biological functions of cancer, identification and validation of therapeutic targets, as well as in vitro or in vivo preclinical drug screening. Here we report there is a frequent loss-of-function of polycomb repressive complex 2 (PRC...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Feng, Helin, Tillman, Heather, Wu, Gang, Davidoff, Andrew M., Yang, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6007463/
https://ncbi.nlm.nih.gov/pubmed/29930752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25484
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