Frequent epigenetic alterations in polycomb repressive complex 2 in osteosarcoma cell lines

Osteosarcoma (OS) cell lines are widely used in understanding the biological functions of cancer, identification and validation of therapeutic targets, as well as in vitro or in vivo preclinical drug screening. Here we report there is a frequent loss-of-function of polycomb repressive complex 2 (PRC...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Feng, Helin, Tillman, Heather, Wu, Gang, Davidoff, Andrew M., Yang, Jun
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2018
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6007463/
https://ncbi.nlm.nih.gov/pubmed/29930752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25484
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