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Lack of JAK2 Activating Non-synonymous Mutations In Diffuse Large B Cell Tumors: JAK2 Deregulation Still Unexplained

Deregulated JAK2 signaling plays an important role in the pathogenesis of myeloproliferative neoplasms (MPN). We and others have shown constitutive activation of JAK2 and STAT3 in diffuse large B cell lymphomas (DLBCL). We sought to determine the mechanism of JAK2 signaling in DLBCL tumors with a ge...

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Bibliografske podrobnosti
Main Authors: Witzig, Thomas E., Price-Troska, Tammy, Stenson, Mary J., Gupta, Mamta
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3951413/
https://ncbi.nlm.nih.gov/pubmed/22762550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/10428194.2012.708931
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