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Regulation of STAT3 by histone deacetylase-3 in diffuse large B-cell lymphoma: implications for therapy

Diffuse large B-cell lymphoma (DLBCL) with an activated B-cell (ABC) gene-expression profile has been shown to have a poorer prognosis compared with tumors with a germinal center B-cell type. ABC cell lines have constitutive activation of STAT3; however, the mechanisms regulating STAT3 signaling in...

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Detalhes bibliográficos
Main Authors: Gupta, M, Han, JJ, Stenson, M, Wellik, L, Witzig, TE
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3625618/
https://ncbi.nlm.nih.gov/pubmed/22116549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2011.340
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