Expression of Myc, but not pSTAT3, is an adverse prognostic factor for diffuse large B-cell lymphoma treated with epratuzumab/R-CHOP

STAT3 regulates cell growth by up-regulating downstream targets, such as Myc. The frequency of phosphorylated STAT3 (pSTAT3) and Myc expression and their prognostic relevance is unknown within diffuse large B-cell lymphoma (DLBCL) germinal center B-cell (GCB) and non-GCB subtypes. pSTAT3 and Myc wer...

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Bibliographische Detailangaben
Hauptverfasser: Gupta, Mamta, Maurer, Matthew J., Wellik, Linda E., Law, Mark E., Han, Jing Jing, Ozsan, Nazan, Micallef, Ivana N., Dogan, Ahmet, Witzig, Thomas E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2012
Schlagworte:
Clinical Trials and Observations
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3507146/
https://ncbi.nlm.nih.gov/pubmed/23018644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-05-428466
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