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A shift from pStat6 to pStat3 predominance is associated with inflammatory bowel disease-associated dysplasia

BACKGROUND: Activated Stat3 is an important mediator of oncogenesis in the colon. To test the hypothesis that select Stat activation and/or the pattern of Stat activation serves as a marker for early neoplastic transformation, we examined the distribution of activated Stat1(pStat1), Stat6(pStat6) an...

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Detalhes bibliográficos
Main Authors: Wick, Elizabeth C., LeBlanc, Robert E., Ortega, Guillermo, Robinson, Chelsea, Platz, Elizabeth, Pardoll, Drew M., Iacobuzio-Donahue, Chris, Sears, Cynthia L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266961/
https://ncbi.nlm.nih.gov/pubmed/22021169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ibd.21908
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