Lactulose and Melibiose Attenuate MPTP-Induced Parkinson’s Disease in Mice by Inhibition of Oxidative Stress, Reduction of Neuroinflammation and Up-Regulation of Autophagy

Parkinson’s disease (PD) is a common neurodegenerative disease characterized by the progressive loss of dopaminergic (DAergic) neurons in the ventral brain. A disaccharide trehalose has demonstrated the potential to mitigate the DAergic loss in disease models for PD. However, trehalose is rapidly hy...

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Udgivet i:Front Aging Neurosci
Main Authors: Lin, Chih-Hsin, Wei, Pei-Cih, Chen, Chiung-Mei, Huang, Yu-Ting, Lin, Jia-Lan, Lo, Yen-Shi, Lin, Jia-Li, Lin, Chung-Yin, Wu, Yih-Ru, Chang, Kuo-Hsuan, Lee-Chen, Guey-Jen
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Neuroscience
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7396622/
https://ncbi.nlm.nih.gov/pubmed/32848705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2020.00226
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