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A distal regulatory region of a class I human histone deacetylase
Histone deacetylases (HDACs) are key enzymes in epigenetics and important drug targets in cancer biology. Whilst it has been established that HDACs regulate many cellular processes, far less is known about the regulation of these enzymes themselves. Here, we show that HDAC8 is allosterically regulat...
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出版年: | Nat Commun |
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主要な著者: | , , , , , , , , , , |
フォーマット: | Artigo |
言語: | Inglês |
出版事項: |
Nature Publishing Group UK
2020
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7395746/ https://ncbi.nlm.nih.gov/pubmed/32737323 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-17610-w |
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