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A distal regulatory region of a class I human histone deacetylase

Histone deacetylases (HDACs) are key enzymes in epigenetics and important drug targets in cancer biology. Whilst it has been established that HDACs regulate many cellular processes, far less is known about the regulation of these enzymes themselves. Here, we show that HDAC8 is allosterically regulat...

詳細記述

保存先:
書誌詳細
出版年:Nat Commun
主要な著者: Werbeck, Nicolas D., Shukla, Vaibhav Kumar, Kunze, Micha B. A., Yalinca, Havva, Pritchard, Ruth B., Siemons, Lucas, Mondal, Somnath, Greenwood, Simon O. R., Kirkpatrick, John, Marson, Charles M., Hansen, D. Flemming
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7395746/
https://ncbi.nlm.nih.gov/pubmed/32737323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-17610-w
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