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Molecular Structure and Function of Janus Kinases: Implications for the Development of Inhibitors
Cytokines can trigger multiple signalling pathways, including Janus tyrosine kinases [JAK] and signal transducers and activators of transcription [STATS] pathways. JAKs are cytoplasmic proteins that, following the binding of cytokines to their receptors, transduce the signal by phosphorylating STAT...
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| Publicado no: | J Crohns Colitis |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7395311/ https://ncbi.nlm.nih.gov/pubmed/32083640 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ecco-jcc/jjz206 |
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