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Molecular Structure and Function of Janus Kinases: Implications for the Development of Inhibitors

Cytokines can trigger multiple signalling pathways, including Janus tyrosine kinases [JAK] and signal transducers and activators of transcription [STATS] pathways. JAKs are cytoplasmic proteins that, following the binding of cytokines to their receptors, transduce the signal by phosphorylating STAT...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Crohns Colitis
Main Authors: Garrido-Trigo, Alba, Salas, Azucena
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7395311/
https://ncbi.nlm.nih.gov/pubmed/32083640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ecco-jcc/jjz206
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