Enhancing Neuraminidase Immunogenicity of Influenza A Viruses by Rewiring RNA Packaging Signals

Humoral immune protection against influenza virus infection is mediated largely by antibodies against hemagglutinin (HA) and neuraminidase (NA), the two major glycoproteins on the virus surface. While influenza virus vaccination efforts have focused mainly on HA, NA-based immunity has been shown to...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Zheng, Allen, Sun, Weina, Xiong, Xiaoli, Freyn, Alec W., Peukes, Julia, Strohmeier, Shirin, Nachbagauer, Raffael, Briggs, John A. G., Krammer, Florian, Palese, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7394900/
https://ncbi.nlm.nih.gov/pubmed/32493826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00742-20
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