Regulation of BMP4/Dpp retrotranslocation and signaling by deglycosylation

During endoplasmic reticulum-associated degradation (ERAD), the cytoplasmic enzyme N-glycanase 1 (NGLY1) is proposed to remove N-glycans from misfolded N-glycoproteins after their retrotranslocation from the ER to the cytosol. We previously reported that NGLY1 regulates Drosophila BMP signaling in a...

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Veröffentlicht in:eLife
Hauptverfasser: Galeone, Antonio, Adams, Joshua M, Matsuda, Shinya, Presa, Maximiliano F, Pandey, Ashutosh, Han, Seung Yeop, Tachida, Yuriko, Hirayama, Hiroto, Vaccari, Thomas, Suzuki, Tadashi, Lutz, Cathleen M, Affolter, Markus, Zuberi, Aamir, Jafar-Nejad, Hamed
Format: Artigo
Sprache:Inglês
Veröffentlicht: eLife Sciences Publications, Ltd 2020
Schlagworte:
Cell Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7394544/
https://ncbi.nlm.nih.gov/pubmed/32720893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.55596
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