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The Functional Role of Voltage-Gated Sodium Channel Nav1.5 in Metastatic Breast Cancer

Voltage-gated sodium channels (VGSCs), which are abnormally expressed in various types of cancers such as breast cancer, prostate cancer, lung cancer, and cervical cancer, are involved in the metastatic process of invasion and migration. Nav1.5 is a pore-forming α subunit of VGSC encoded by SCN5A. V...

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Bibliografske podrobnosti
izdano v:Front Pharmacol
Main Authors: Luo, Qianxuan, Wu, Ting, Wu, Wenfang, Chen, Gong, Luo, Xuan, Jiang, Liping, Tao, Huai, Rong, Mingqiang, Kang, Shuntong, Deng, Meichun
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7393602/
https://ncbi.nlm.nih.gov/pubmed/32792949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.01111
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