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RAF and MEK inhibitor therapy in adult patients with brain tumors: a case-based overview and practical management of adverse events

AbstractTargeted therapy has gained mainstream attention with notable successes against specific genetic mutations in many cancers. One particular mutation, the BRAF V600E mutation, is present in a small subset of gliomas in adults. Although clinical experience and trial data of RAF-targeted therapy...

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Detalhes bibliográficos
Publicado no:Neurooncol Pract
Main Authors: Schreck, Karisa C, Patel, Mallika P, Wemmer, Jan, Grossman, Stuart A, Peters, Katherine B
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7393273/
https://ncbi.nlm.nih.gov/pubmed/32765888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nop/npaa006
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