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BRAF Mutations and the Utility of RAF and MEK Inhibitors in Primary Brain Tumors

BRAF mutations have been identified as targetable, oncogenic mutations in many cancers. Given the paucity of treatments for primary brain tumors and the poor prognosis associated with high-grade gliomas, BRAF mutations in glioma are of considerable interest. In this review, we present the spectrum o...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Schreck, Karisa C., Grossman, Stuart A., Pratilas, Christine A.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6769482/
https://ncbi.nlm.nih.gov/pubmed/31466300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11091262
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