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Synaptic RTP801 contributes to motor-learning dysfunction in Huntington’s disease
RTP801/REDD1 is a stress-responsive protein that mediates mutant huntingtin (mhtt) toxicity in cellular models and is up regulated in Huntington’s disease (HD) patients’ putamen. Here, we investigated whether RTP801 is involved in motor impairment in HD by affecting striatal synaptic plasticity. To...
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| Publicado no: | Cell Death Dis |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7392897/ https://ncbi.nlm.nih.gov/pubmed/32732871 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-02775-5 |
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