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Reduced Fractalkine Levels Lead to Striatal Synaptic Plasticity Deficits in Huntington’s Disease

Huntington’s disease (HD) is an inherited neurodegenerative disorder in which the striatum is the most affected brain region. Although a chronic inflammatory microglial reaction that amplifies disease progression has been described in HD patients, some murine models develop symptoms without inflamma...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: Kim, Anya, García-García, Esther, Straccia, Marco, Comella-Bolla, Andrea, Miguez, Andrés, Masana, Mercè, Alberch, Jordi, Canals, Josep M., Rodríguez, Manuel J.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7314984/
https://ncbi.nlm.nih.gov/pubmed/32625064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2020.00163
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