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Reduced Fractalkine Levels Lead to Striatal Synaptic Plasticity Deficits in Huntington’s Disease

Huntington’s disease (HD) is an inherited neurodegenerative disorder in which the striatum is the most affected brain region. Although a chronic inflammatory microglial reaction that amplifies disease progression has been described in HD patients, some murine models develop symptoms without inflamma...

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Podrobná bibliografie
Vydáno v:Front Cell Neurosci
Hlavní autoři: Kim, Anya, García-García, Esther, Straccia, Marco, Comella-Bolla, Andrea, Miguez, Andrés, Masana, Mercè, Alberch, Jordi, Canals, Josep M., Rodríguez, Manuel J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7314984/
https://ncbi.nlm.nih.gov/pubmed/32625064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2020.00163
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