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Direct Cytosolic Delivery of Proteins Through Co-Engineering of Proteins and Polymeric Delivery Vehicles

Nanocarrier-mediated protein delivery is a promising strategy for fundamental research and therapeutic applications. However, the efficacy of current platforms for delivery into cells is limited by endosomal entrapment of delivered protein cargo, with concomitantly inefficient access to the cytosol...

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Podrobná bibliografie
Vydáno v:J Am Chem Soc
Hlavní autoři: Lee, Yi-Wei, Luther, David C., Goswami, Ritabrita, Jeon, Taewon, Clark, Vincent, Elia, James, Gopalakrishnan, Sanjana, Rotello, Vincent M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7392052/
https://ncbi.nlm.nih.gov/pubmed/32049533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.9b12759
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