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Accessing intracellular targets through nanocarrier-mediated cytosolic protein delivery
Protein-based therapeutics have unique therapeutic potential due to their specificity, potency, and low toxicity. The vast majority of intracellular applications of proteins require access to the cytosol. Direct entry to the cytosol is challenging due to the impermeability of the cell membrane to pr...
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| Опубликовано в: : | Trends Pharmacol Sci |
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| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7502523/ https://ncbi.nlm.nih.gov/pubmed/32891429 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2020.08.005 |
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