Increased intracellular Cl(-) concentration improves airway epithelial migration by activating the RhoA/ROCK Pathway

In the airway, Cl(-) is the most abundant anion and is critically involved in transepithelial transport. The correlation of the abnormal expression and activation of chloride channels (CLCs), such as cystic fibrosis transmembrane conductance regulators (CFTRs), anoctamin-1, and CLC-2, with cell migr...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Theranostics
Autori principali: Huang, Wenjie, Tan, Meiling, Wang, Yue, Liu, Lei, Pan, Yan, Li, Jingjing, Ouyang, Mingxing, Long, Chunjiao, Qu, Xiangping, Liu, Huijun, Liu, Chi, Wang, Jia, Deng, Linhong, Xiang, Yang, Qin, Xiaoqun
Natura: Artigo
Lingua:Inglês
Pubblicazione: Ivyspring International Publisher 2020
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7392015/
https://ncbi.nlm.nih.gov/pubmed/32754261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.46002
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