Increased intracellular Cl(-) concentration improves airway epithelial migration by activating the RhoA/ROCK Pathway

In the airway, Cl(-) is the most abundant anion and is critically involved in transepithelial transport. The correlation of the abnormal expression and activation of chloride channels (CLCs), such as cystic fibrosis transmembrane conductance regulators (CFTRs), anoctamin-1, and CLC-2, with cell migr...

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Bibliographische Detailangaben
Veröffentlicht in:Theranostics
Hauptverfasser: Huang, Wenjie, Tan, Meiling, Wang, Yue, Liu, Lei, Pan, Yan, Li, Jingjing, Ouyang, Mingxing, Long, Chunjiao, Qu, Xiangping, Liu, Huijun, Liu, Chi, Wang, Jia, Deng, Linhong, Xiang, Yang, Qin, Xiaoqun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Ivyspring International Publisher 2020
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7392015/
https://ncbi.nlm.nih.gov/pubmed/32754261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.46002
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